What is a laboratory PSM?
The PSM laboratory (Microbiological Safety Cabinet) is a protective device used in microbiology, molecular biology, pharmacy or medical research laboratories. It provides three levels of protection:
- User protection against inhalation of pathogens.
- Protection of the sample against external contamination.
- Environmental protection by filtering the extracted air.
Thanks to high-efficiency HEPA filters and controlled laminar flow, the PSM considerably limits the risks of dissemination of infectious aerosols into the ambient air.
Why use a laboratory PSM?
Using a laboratory PSM is essential when working with:
- Class 2 or 3 pathogens (e.g. viruses, bacteria, parasites).
- Sensitive biological samples (blood, DNA, RNA).
- Research work in molecular biology .
- Sterile pharmaceutical products requiring high protection.
Whether it is to limit cross-contamination, protect the handler against infections or secure a laboratory hood protocol, the PSM is now essential in the prevention of biological risks.
The different types of laboratory PSM
There are several categories of laboratory PSM adapted to different risk levels:
Class I PSM
Protects the user only. The exhaust air passes through a HEPA filter but the product is not protected from external contamination.
Class II PSM
Provides triple protection: sample, handler, and environment. It is most commonly used in modern laboratories.
Class III PSM
Designed for absolute containment, it is completely airtight and equipped with integrated handling gloves. Used for highly pathogenic biological agents (class 4).
The choice of type depends on the risks associated with the products handled and the protocols in force in your establishment.
What is a laboratory PSM used for?
A PSM laboratory is based on several technological principles:
- Front suction : captures aerosols and particles generated during handling.
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Blows HEPA filtered air over the work surface to create a sterile laminar flow.
- HEPA filtration of extracted air to prevent any contamination of the outside environment.
- Plenum depression to prevent any leakage to the outside.
Some models are also equipped with a UV lamp to ensure automatic disinfection of the workspace between two operations.
Who is the use of a laboratory PSM intended for?
The PSM laboratory is used in many scientific and industrial fields:
- Hospital laboratories for microbiological diagnostics (e.g. COVID-19, tuberculosis).
- Research laboratories working on human or animal pathogens.
- Pharmaceutical industry for the manufacture of sterile drugs and vaccines.
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Biotechnology laboratories for the manipulation of sensitive cell cultures.
- Quality control laboratories for microbiological analysis of food, cosmetics or drinking water.
In summary, any structure handling potentially dangerous microorganisms has an obligation to protect its teams and its environment with an appropriate PSM.
PSM laboratory price: how much should you budget?
The PSM laboratory represents an essential investment to ensure laboratory safety. The price depends on several factors:
- PSM class : A Class II PSM generally costs more than a Class I model due to its triple protection.
- Size : The larger the work volume, the more expensive the equipment.
- Options : LED lighting, airflow alarms, integrated electrical outlets, controlled laminarity, etc.
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The brand : renowned manufacturers such as Noroit, Faster and Thermo Fisher offer high-end models.
- Compliance with standards : NF EN 12469, ISO 14644, HEPA filtration criteria, etc.
On average:
- A Class I PSM costs between €4,000 and €7,000.
- A standard Class II PSM costs between €6,000 and €15,000 depending on dimensions and options.
- A very specific Class III PSM can exceed €25,000.
At Rewake, we also offer reconditioned laboratory fume hoods and PSMs at discounted prices, saving you up to 60% without compromising on safety.
Maintenance and upkeep of a laboratory PSM
To maintain the full efficiency of a PSM laboratory , rigorous maintenance is essential:
Regular replacement of HEPA filters
A saturated HEPA filter can compromise protection. Generally, replacement every 12 to 24 months is recommended depending on usage and dust levels.
Annual airflow check
Airflow, laminar velocity and sealing control are mandatory to ensure the station complies with biosafety standards.
Cleaning and disinfection
The work surface, walls and visor must be cleaned daily with suitable products, without aggressive solvents which could damage the filters or stainless steel surfaces.
Calibration of alarms and ventilation systems
Flow and malfunction alarms must be functional to prevent any risk in the event of a technical anomaly.
Annual professional maintenance is strongly recommended to extend the lifespan of your PSM and ensure optimal protection for your teams.
How to choose your PSM laboratory?
The choice of a PSM laboratory depends on several criteria:
- Nature of the biological agents handled : class 2, 3 or 4 pathogens.
- Required work area : number of samples handled simultaneously.
- Safety standards required by your sector (pharmaceutical, hospital, research, etc.).
- Room configuration : available space, ambient airflow, power supply.
- Available budget : purchase new or reconditioned depending on your laboratory's resources.
At Rewake, we help you define the model adapted to your specific use, taking into account the technical and regulatory constraints of your working environment.
